Synergies for Cancer Treatment
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Cell signalling
Hypoxia Signaling
https://www.cellsignal.com/pathways/hypoxia-signaling-pathway
Wnt/β-Catenin Signaling
https://www.cellsignal.com/pathways/wnt-beta-catenin-signaling-pathway
PI3K / Akt Signaling
https://www.cellsignal.com/pathways/pathways-akt-signaling
Notch Signaling
https://www.cellsignal.com/pathways/notch-signaling-pathway
TGF-β Signaling
https://www.cellsignal.com/pathways/tgf-beta-signaling-pathway
GSK3 Signaling
{
ref
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https://www.thermofisher.com/cl/es/home/life-science/antibodies/antibodies-learning-center/antibodies-resource-library/cell-signaling-pathways/gsk3-signaling-pathway.html
ErbB/HER Signaling
https://www.cellsignal.com/pathways/erbb-her-signaling?_requestid=456880
Molecular Landscapes
Digizyme - Knowledge Through Visual Science
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Drug Repurposing Strategies in Oncology
Drug Repurposing Drug repurposing involves discovering new uses for existing, clinically approved drugs. This approach offers several key ad...
Theory of Cancer
According to the prevailing accepted theory of carcinogenesis { ref }, the somatic mutation theory, cancer arises when cells acquire many ge...
Synergistic Anticancer Effects of Diclofenac and Metformin
Repurposing non-oncology drugs for cancer treatment has become an area of increasing interest. In particular, combinations of well-known pha...
Repurposing Phenylbutyrate: versatile anticancer agent
Phenylbutyrate (PB), a short-chain fatty acid derivative, is primarily recognized as an ammonia scavenger and histone deacetylase inhibitor ...
Combination of RAS(ON) G12C-selective inhibitors with SHP2 inhibitors to sensitize tumours to immune checkpoint blockade
Lung cancer driven by KRAS mutations, particularly the G12C variant, remains a significant challenge in non-small cell lung cancer (NSCLC) t...
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