Herbs with potential anticancer properties

  1. Anise: Anethole {study}
  2. Ashitaba: also known as Japanese parsley, contains high levels of chlorophyll & Vit. B12.🛈
  3. Ashwagandha: contains Withaferin A, a potent anti-cancer agent and ferroptosis inducer ðŸ›ˆ Testosterone ▲.Cortisol ▼
  4. Basil: Nevadensin (Hippo pathway activation)
  5. Black walnut: Juglone
  6. Bloodroot: Sanguinarine is the principal alkaloid found in the extract of bloodroot {review}
  7. Burdock root: lignans from A. lappa exhibit antiproliferative and apoptotic effects over leukemic cells and  pancreatic cancer cell lines {ref} RA {ref}
  8. Boldo: boldine
  9. Cardamom:  PI3K-Akt ▼
  10. Calendula {ref ⏐ref}
  11. Cat’s Claw: Uncaria tomentosa, effective adjuvant treatment in reducing adverse chemotherapy effects {study}.(TOA-free Cat's Claw) LDHA ▼
  12. Cayenne: Capsaicin
  13. Chamomile is good for the thyroid, Hypoglycaemic effect in combination with oregano, anti-diarrhoeal in combination with anise. Cortisol ▼
  14. Chelidonium majus:
  15. Cinnamomum cassia: inhibition of NFκB and AP1{study}. carbonic anhydrase inhibitor
  16. Cinnamomum verum (Ceylon) Glutaminase inhibition (ammonia activates glutaminase)
  17. Clitoria Ternatea (Butterfly Pea) {study}
  18. Coriander: also known as cilantro.
  19. Dandelion: inhibit cancer cell proliferation by activating AMPK {study}. Liver and kidney, support, anemia.
  20. Echinacea: contains Caftaric acid and 2-O-Feruloyl tartaric acid (HER2 inhibitors)
  21. Feverfew:(possible estrogenic effect) anti-inflammatory. Parthenolide. DNMT + NRF2 inhibitor.
  22. Fenugreek:Trigonelline NRF2 inhibitor
  23. Galium aparine: also known as cleavers, clivers, goosegrass.
  24. Galla Chinensis LDHA ▼
  25. Garlic: myricetin, allicin
  26. Ginger: salicylate, 6-Shogaol (dried ginger) Testosterone ▲
  27. Holy Basil: also called Tulsi. Contains linalool. In the morning on empty stomach. Cortisol ▼ Testosterone ▲
  28. Licorice: protective activity against liver toxicity, anticancer properties, estrogen ▼, testosterone T▼, blood pressure▲ AKR1C1 ▼
  29. Lemon balm: rosmarinic acid
  30. Lemongrass cymbopogon citratus {ref}
  31. Honeybush: contains Mangiferin {study}
  32. Melaphis Chinensis LDH-A inhibition
  33. Milk Thistle: also known as Silymarin. Liver support.
  34. Mint: contains linalool shown to have anti-cancer effects. Rosmarinic acid
  35. Mulberry leaves
  36. Neem: also called Azadirachta indica {review}
  37. Nettle: {article} estrogen blocker {study} LOX inhibitor, supports kidney health, supports thyroid and pituitary glands, anemia.  
  38. Oregano: luteolin, Carnosic acid, rosmarinic acid. Carvacrol.
  39. Pau D'Arco: anticancer, antiviral, antibacterial (H.Pylori), antifungal. Potential anti-vitamin K effect. Estrogen ▼
  40. Parsley: herb of the carrot family (also called parsley family; Apiaceae), contains apigenin, vitamin K, detox, thyroid {ref} PI3K-Akt-mTOR ▼
  41. Plantain
  42. Purslane: {article}
  43. Rabdosia rubescens: oridonin
  44. Red clover:  Biochanin A, formononetin (estrogenic, avoid using in hormonal cancers)
  45. Rhodiola: also known as Arctic or Golden Root. Testosterone ▲ Salidroside PI3K-Akt-mTOR ▼ {study} LDHA ▼
  46. Rhubarb Extract: contains emodin {study} and parietin {article}
  47. Rosemary: carnosol {study} → withafarin A {study} HDAC2 modulation {review} Helps break down estrogen, Carnosic acid (Carnosic acid biosynthesis and accumulation take place exclusively in young rosemary leaves at the branch apices, with the diterpene molecule being partially consumed during leaf development and aging ref ).β-CAT Rosmarinic acid, Rosmaricine, carbonic anhydrase inhibition. JAK inhibition. p-Coumaric acid   → Betulinic Acid HIF ST3. Luteolin and apigenin inhibit the efflux of rosmarinic acid. → with Citric acid to inhibit iron uptake.
  48. Rooibos Cortisol ▼ {ref}
  49. Ruta graveolens {glioblastoma}
  50. Saffron:     Crocetin {review} → curcumin
  51. Salacia
  52. Schisandra
  53. Scutellaria baicalensis (Chinese Skullcap): Baicalein, Baicalin, Nevadensin 
  54. Scutellaria barbata: inhibition of OXPHOS but also of glycolysis {study}
  55. Shatavari
  56. Suma
  57. Thyme: Thyme strengthens the immune system. Thymol. Carvacrol. Thymohydroquinone {ref}
  58. Triphala: chebulinic acid VEGF inhibition. Triphala demonstrated significant immunostimulatory effects on cytotoxic T cells (CD3−CD8+) and natural killer cells (CD16+CD56+){ref}.Cortisol ▼
  59. Toxicodendron vernicifluum {article}
  60. Valerian

Medicinal plant species with significant amounts of phytomelatonine {ref}

Common Name/Species  Phytomelatonin Content (ng·g−1 DW)
========================================================
Thyme/Thymus vulgaris L.                 38,000
Chinese liquorice/Glycyrrhiza uralensis Fisch. 34,000
Sage/Salvia officinalis L. (Carnosic acid)         29,000
St. John’s wort/Hypericum perforatum L. 23,000
Peppermint/Mentha piperita                 19,500
Cat’s claw herb/Uncaria rhynchophylla Miq.         2460
Tokyo violet/Viola philipica Cav.                 2360
Feverfew/Tanacetum parthenium L.         1700
Mulberry/Morus alba L.                 1510

Supplements should only be taken under the supervision of a healthcare provider. Supplements or herbal preparations should never be combined with chemotherapy, radiotherapy, immunotherapy, or any other cancer treatment unless the safety and efficacy of such combination is established. It's especially important to make sure anything you add to the standard treatment will further improve the effectiveness of that treatment, hence the importance of discussing any addition of supplements or dietary interventions during active cancer treatment with the oncologist. When you use a new herb or supplement, start dosing with the smallest amount.



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