Herbs in cancer treatment

1. Anise: Anethole {study}
2. Ashitaba: also known as Japanese parsley, contains high levels of chlorophyll & Vit. B12.🛈
3. Ashwagandha: contains Withaferin A, a potent anti-cancer agent and ferroptosis inducer 🛈 Testosterone ▲.Cortisol ▼
4. Black walnut: Juglone
5. Bloodroot: Sanguinarine is the principal alkaloid found in the extract of bloodroot {review}
6. Burdock: lignans from A. lappa exhibit antiproliferative and apoptotic effects over leukemic cells and  pancreatic cancer cell lines
7. Boldo: boldine
8. Cardamom:  PI3K-Akt ▼
9. Calendula {ref ⏐ref}
10. Cat’s Claw: Uncaria tomentosa, effective adjuvant treatment in reducing adverse chemotherapy effects {study}.(TOA-free Cat's Claw) LDHA ▼
11. Cayenne: Capsaicin
12. Chamomile is good for the thyroid, Hypoglycaemic effect in combination with oregano, anti-diarrhoeal in combination with anise. Cortisol ▼
13. Chelidonium majus:
14. Cinnamomum cassia: inhibition of NFκB and AP1{study}. carbonic anhydrase inhibitor
15. Clitoria Ternatea (Butterfly Pea) {study}
16. Coriander: also known as cilantro.
17. Dandelion: inhibit cancer cell proliferation by activating AMPK {study}. Liver and kidney, support, anemia.
18. Echinacea: contains Caftaric acid and 2-O-Feruloyl tartaric acid (HER2 inhibitors)
19. Feverfew:(possible estrogenic effect) anti-inflammatory. DNMT inhibitor
20. Fenugreek:
21. Galium aparine: also known as cleavers, clivers, goosegrass.
22. Galla Chinensis LDHA ▼
23. Garlic: myricetin, allicin
24. ⭐ Ginger: salicylate, 6-Shogaol (dried ginger) Testosterone ▲
25. ⭐ Holy Basil: also called Tulsi. Contains linalool. In the morning on empty stomach, with honey. Cortisol ▼ Testosterone ▲
26. Licorice: protective activity against liver toxicity, anticancer properties, estrogen ▼, testosterone T▼, blood pressure▲ AKR1C1 ▼
27. Lemon balm: rosmarinic acid
28. Lemongrass cymbopogon citratus {ref}
29. Honeybush: contains Mangiferin {study}
30. Melaphis Chinensis LDH-A inhibition
31. Milk Thistle: also known as Silymarin. Liver support.
32. Mint: contains linalool shown to have anti-cancer effects. Rosmarinic acid
33. Neem: also called Azadirachta indica {review}
34. ⭐ Nettle: {article} estrogen blocker {study} LOX inhibitor, supports kidney health, supports thyroid and pituitary glands, anemia.  
35. ⭐ Oregano: luteolin, Carnosic acid, rosmarinic acid. Carvacrol.
36. Pau D'Arco: anticancer, antiviral, antibacterial (H.Pylori), antifungal. Potential anti-vitamin K effect. Estrogen ▼
37. ⭐ Parsley: herb of the carrot family (also called parsley family; Apiaceae), contains apigenin, vitamin K, detox, thyroid {ref} PI3K-Akt-mTOR ▼
38. Plantain
39. Purslane: {article}
40. Rabdosia rubescens: oridonin
41. Red clover:  Biochanin A, formononetin
42. ⭐ Rhodiola: also known as Arctic or Golden Root. Testosterone ▲ Salidroside PI3K-Akt-mTOR ▼ {study} LDHA ▼
43. Rhubarb Extract: contains emodin {study} and parietin {article}
44. ⭐ Rosemary: carnosol {study} HDAC2 modulation {review} Helps break down estrogen, Carnosic acid (Carnosic acid biosynthesis and accumulation take place exclusively in young rosemary leaves at the branch apices, with the diterpene molecule being partially consumed during leaf development and aging ref ). Rosmarinic acid, Rosmaricine, carbonic anhydrase inhibition. JAK inhibition. p-Coumaric acid   → Betulinic Acid HIF ST3. Luteolin and apigenin inhibit the efflux of rosmarinic acid.
45. Rooibos Cortisol ▼ {ref}
46. Ruta graveolens {glioblastoma}
47. Saffron: Crocetin {review} → curcumin
48. Salacia
49. Schisandra
50. Scutellaria barbata: inhibition of OXPHOS but also of glycolysis {study}
51. Shatavari
52. Sheep Sorrel
53. Suma
54. ⭐ Thyme: Thyme strengthens the immune system. Thymol. Carvacrol. Thymohydroquinone {ref}
55. Triphala: chebulinic acid VEGF inhibition. Triphala demonstrated significant immunostimulatory effects on cytotoxic T cells (CD3−CD8+) and natural killer cells (CD16+CD56+){ref}.Cortisol ▼
56. Toxicodendron vernicifluum {article}
57. Valerian

Phytomelatonin: medicinal plant species with phytomelatonin contents above 100 ng/g tissue{Ref}

Common Name/Species  Phytomelatonin Content (ng·g−1 DW)

========================================================

Thyme/Thymus vulgaris L.                 38,000

Chinese liquorice/Glycyrrhiza uralensis Fisch. 34,000

Sage/Salvia officinalis L. (Carnosic acid)         29,000

St. John’s wort/Hypericum perforatum L. 23,000 LOX inhibitor

Peppermint/Mentha piperita                 19,500

Cat’s claw herb/Uncaria rhynchophylla Miq.         2460

Tokyo violet/Viola philipica Cav.                 2360

Feverfew/Tanacetum parthenium L.         1700

Mulberry/Morus alba L.                 1510

Aloe/Aloe vera L.                         516

Clove/Syzygium aromaticum L.          446

Yarrow/Achillea millefolium L.                 340

Figwort/Scrophularia ningpoensis Hemsl. 342

Korean mint/Agastache rugosa Kuntz.         300

Qin Jiao/Gentiana macrophylla Pall.         180

Scullcap/Scutellaria amoena C.H. Wright 178

Japanese honeysuckle/Lonicea japonica Thunb 140

Curcuma/Curcuma aeruginosa Roxb.         120

Herbal Mixtures

• Deep Immune® {ref}
• Zyflamend™ {ref}

Salus Ortie (nettle extract)

Antifungal efficacy of herbs

Herbal extracts of Lawsonia inermis (Henna), Withania somnifer (or Ashwagandha), Curcuma longa (or Turmeric), Cymbopogon citrates( or Lemongrass) and Zingiber officinale(or Ginger) give the best inhibitory effect and they have the potential to control the growth of Candida albicans. {study}

A mixture of 5 herbal extracts (pumpkin  seeds, purple turmeric, pearl barley, corn pistil, and cinnamon) that induce type I interferons through Toll-like receptor 4 signaling {ref}

Ashwagandha + Ginseng: Aliper A, Jellen L, Cortese F, Artemov A, Karpinsky-Semper D, Moskalev A, Swick AG, Zhavoronkov A. Towards natural mimetics of metformin and rapamycin. Aging (Albany NY). 2017 Nov 15;9(11):2245-2268. doi: 10.18632/aging.101319. PMID: 29165314; PMCID: PMC5723685.

Supplements should only be taken under the supervision of a healthcare provider. Supplements or herbal preparations should never be used in combination with chemotherapy, radiotherapy, immunotherapy, or any other cancer treatment unless the safety and efficacy of such combination is established. It's especially important to make sure anything you add to the standard treatment will further improve the efficacy of that treatment, hence the importance of discussing any addition of supplements or dietary interventions during active cancer treatment with the oncologist.

📌 When you use a new herb or supplement start dosing with the smallest amount.

References & Sources

• http://umm.edu/health/medical/altmed/herb/cats-claw
• http://pubs.sciepub.com/ajps/1/6/1/
• https://www.ncbi.nlm.nih.gov/pubmed/26503998
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1193558/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995283/
• http://ologyjournals.com/jnfrt/jnfrt_00016.pdf
• http://www.maharishiayurvedaindia.org/blog/Cancer.html
• https://strictlymedicinalseeds.com/
• https://sirjasonwinters.com/product/classic-blend-herbal-tea-5oz-with-sage/
• Lyme disease treatment: 2 herbal compounds may beat antibiotics
• https://www.researchgate.net/publication/315742594_An_overview_of_anticancer_activity_of_Garcinia_and_Hypericum
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467149/
• https://www.researchgate.net/publication/262560479_Estimating_the_Yin-Yang_Nature_of_Western_Herbs_A_Potential_Tool_Based_on_Antioxidation-_Oxidation_Theory
• Malongane, Florence & Mcgaw, Lyndy & Mudau, Fhatuwani. (2017). The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: A review. Journal of the science of food and agriculture. 97. 10.1002/jsfa.8472. {Review}
• Can Urtica dioica supplementation attenuate mercury intoxication in Wistar rats?
• https://www.cannabisclinicians.org/2021/12/23/synergy-with-cannabis-and-other-herbs-thinking-beyond-plant-constituents/
• https://bigbudsmag.com/the-best-medicinal-herbs-used-with-cannabis/
• https://www.sciencedirect.com/book/9780128190920/toxicology
• The synergistic potential of various teas, herbs and therapeutic drugs in health improvement: A review
• https://www.ad.nl/binnenland/waarschuwing-neem-deze-tien-kruiden-nooit-in-met-medicijnen~aebccaf3/
• https://www.thewildpharma.co.uk/common-ailments/salivary-glands
• A guide to the interactions of herbal medicines, dietary supplements and nutraceuticals with conventional medicines
• http://www.beta-lapachone.com/
• The Tropical Plant Database
• https://www.researchgate.net/publication/292947920_Synergy_in_Herbal_Medicines_Part_1
• Synergistic Herb Interactions with Anticancer Drugs {ref}
• https://catscientific.com/homogenizer-drives/unidrive-x1000d-homogenizer-drive-with-digital-display/
• https://www.hielscher.com/ultrasonic-cannabis-oil-emulsion.htm

"Fear less, hope more; Eat less, chew more; Whine less, breathe more; Talk less, say more; Love more and all good things will be yours" Swedish proverb."

Tags: botanicals, versatile phytomedicines, herbal remedies, herbal supplements, medicinal plants, anticancer herbs