Several studies have suggested that Graviola is able to inhibit the growth of cancer cells by targeting different cell signaling pathways. One such pathway is the PI3K/Akt/mTOR pathway, which is known to be involved in the development and progression of cancer. Several studies have found that Graviola extract can inhibit the activity of this pathway, which may in turn lead to the inhibition of cancer cell growth.
Patient with Metastatic Breast Cancer Achieves Stable Disease for 5 Years on Graviola and Xeloda after Progressing on Multiple Lines of Therapy {case report}
HIF-1α, NF-κB, GLUT1, GLUT4 and LDHA downregulation {ref}
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