Pterostilbene

100% Trans-Pterostilbene

• Pterostilbene has inhibitory effects on almost every cellular event that promotes tumor progression toward metastasis in apoptosis-dependent as well as apoptosis-independent manners. Most importantly, Pterostilbene, upon oral administration, is able to simultaneously prevent colonization of CTCs and diminish the already established secondary tumor masses in distant organs, greatly lowering the risks of patients for metastatic recurrence due to drug-resistance. Accordingly, Pterostilbene is an ideal choice of alternative medicine to be administered as nutritional supplements. (Full text)

• Pterostilbene could be used in combination with radiation therapy to prevent the generation of CSCs and possibly leads to an improved outcome in HCC patients
• Pterostilbene lowers mitochondrial membrane potential

References and Sources

• https://www.ncbi.nlm.nih.gov/pubmed/22099605
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276376/
• https://iubmb.onlinelibrary.wiley.com/doi/epdf/10.1002/biof.1398
• https://www.hindawi.com/journals/ecam/2013/258425/
• http://www.mdpi.com/1422-0067/19/1/287/htm
• Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis {ref}