Sulforaphane is a naturally occurring compound in cruciferous vegetables like broccoli, Brussels sprouts, and cabbage.
In laboratory studies, sulforaphane has been shown to be a potent HDAC inhibitor, with the ability to reduce HDAC activity by up to 40%. It has also been shown to induce the expression of genes involved in the regulation of cancer cell growth and death.
Potent activator of Nrf2 {ref}
Intermittent use may be safest/most effective e.g. twice a week.
Caution: Sulforaphane may interfere with immunotherapy by immune checkpoint inhibitors (e.g., CTLA-4 antibodies and PD-1/PD-L1 antibodies) or CAR (chimeric antigen receptors) T-cells in cancer patients, and a combination of both treatments may not be advisable. {ref}
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