Xylo-oligosaccharides (XOS) exhibit immunomodulatory, antioxidant, and anti-inflammatory activities that contribute to anticancer effects, particularly against breast and colon cancers by suppressing carcinoma cells. A study showed XOS outperformed fructooligosaccharides in inhibiting precancerous lesions in rats, boosting bifidobacteria, and reducing viable cell counts via MTT assay. Another highlighted cytotoxic effects on HCT-116 (colon) and MCF-7 (breast) cell lines. Mechanisms involve stability in the gut, probiotic stimulation, and reduced lipid peroxidation with increased glutathione-S-transferase and catalase activities in colonic mucosa and liver.
XOS can reduce blood ammonia levels. This effect is attributed to XOS's prebiotic properties, which promote beneficial gut bacteria (e.g., bifidobacteria) that enhance nitrogen metabolism and ammonia detoxification in the intestines, preventing its absorption into the bloodstream.
No comments:
Post a Comment