The cancer-fighting properties of Cannabis.

Beta-Caryophyllene (BCP)

β-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models {study}.

Naturally found in copaiba, basil, cinnamon, cloves, lavender, oregano, rosemary, pepper, and cannabis (East Coast Sour Diesel).

Cannabidiol (CBD)

Reduces ammonia {ref}

Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review

Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies {ref}

Cannabidiol Inhibits angiogenesis by multiple mechanisms {ref}

Cannabidiol (CBD) as a Promising Anti-Cancer Drug {ref}

Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms {ref}

Characterization of P-glycoprotein inhibition by cannabinoids {ref}

Cannabigerol (CBG)

Cannabigerol Is a Potential Therapeutic Agent in a Novel Combined Therapy for Glioblastoma {ref}

Limonene

Strains High in Limonene: Lifter. Elektra. Sour Space Candy. Suver Haze.

Synergy

Synergistic anticancer activity of cannabinoids and beta-caryophyllene in xenograft mouse model of triple negative breast cancer {study}  "It was found that the cytotoxic potential of combinations of cannabinoids with BC increased by 10 folds in comparison to their individual anticancer activity. The combinations that exhibit synergistic action were determined from combination index (CI) values using compusyn software. Other assays such as colony formation, wound healing, apoptotic assay, cell cycle analysis by flow cytometry elucidated the possible mechanism underlying the synergism of the combinations investigated. CBC+BC was proven to be the most potent combination from all the in-vitro studies and hence was further evaluated in in-vivo tumor xenografts. Briefly, 5 million MDA MB 231 DOX RT cells were injected by S.C route in the right flank region of BALB/c nude mice. The animals were treated after the tumor volume reached 180-200mm3. The animals were administered CBC (15mg/kg, i.p.), BC (100mg/kg, i.p.) and CBC+BC thrice a week for two weeks. The tumor volume in the combination group was reduced by 2 folds relative to individual treatments and 4 folds relative to control. "