References: Ammonia in Cancer - The Hidden Oncometabolite Driving Multiple Hallmarks

Hallmarks of Cancer: New Dimensions | Cancer Discovery AACR Journals

New Dimensions in Cancer Biology: Updated Hallmarks of Cancer Published AACR

Hallmarks of Cancer: New Dimensions ResearchGate

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Hallmarks of cancer: the next generation PubMed - NIH

Glutamine metabolism and ammonia death: targeted modulation for enhanced cancer immunotherapy ResearchGate

Novel roles of ammonia in physiology and cancer PMC - PubMed Central

Ammonia as a critical metabolic modulator of anti-tumor immunity PMC - NIH

Glutamine Metabolism in Cancer: Understanding the Heterogeneity PubMed Central

Targeting Glutaminolysis: New Perspectives to Understand Cancer Development and Novel Strategies for Potential Target Therapies Frontiers

The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease PMC

Physiological Role of Glutamate Dehydrogenase in Cancer Cells Frontiers

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures PMC

The differential regulation of the urea cycle in tumors goes awry PubMed

Ammonia in cancer: dual roles and therapeutic strategies ResearchGate

Microbial metabolites in colorectal tumorigenesis and cancer therapy Taylor & Francis Online

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Microbiome and colorectal carcinogenesis: Linked mechanisms and racial differences NIH

Microenvironmental Ammonia Enhances T Cell Exhaustion in Colorectal Cancer PMC

Fusobacterium nucleatum Is Associated with Tumor Characteristics, Immune Microenvironment, and Survival in Appendiceal Cancer MDPI

Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB PMC - NIH

The expression profile of RNA sensors in colorectal cancer and its correlation with cancer stages AME Publishing Company

Uptake Transporters of the SLC21, SLC22A, and SLC15A Families in Anticancer Therapy—Modulators of Cellular Entry or Pharmacokinetics? MDPI

The Solute Carrier (SLC) Transporter Superfamily as Therapeutic Targets for the Treatment of Head and Neck Squamous Cell Carcinoma NIH

Mechanisms of ammonia and ammonium transport by rhesus-associated glycoproteins PMC - NIH

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass PMC - PubMed Central

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass ResearchGate

Nothing Wasted Harvard Medical School

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass PubMed

Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR PLOS One

mTOR Pathways in Cancer and Autophagy PMC - PubMed Central

mTORC1 as the main gateway to autophagy Portland Press - Essays in Biochemistry

The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling PMC - NIH

Unveiling ammonia-induced cell death: a new frontier in clear cell renal cell carcinoma prognosis Frontiers

Glutamine metabolism and ammonia death: targeted modulation for enhanced cancer immunotherapy PMC - PubMed Central

Ammonia-induced lysosomal and mitochondrial damage: a novel perspective on T cell-based cancer immunotherapy PMC - PubMed Central

Novel roles of ammonia in physiology and cancer Journal of Molecular Cell Biology - Oxford Academic

Ammonia metabolism and ammonia-induced cell death: role in cancer therapy PMC

Ammonia-induced lysosomal and mitochondrial damage causes cell death of effector CD8 T cells ResearchGate

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer PubMed

Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin Cancer Research - AACR Journals

Ammonia inhibits antitumor activity of NK cells by decreasing mature perforin bioRxiv

Ammonia as a critical metabolic modulator of anti-tumor immunity ResearchGate

Tumor-Associated Macrophages in Tumor Immunity Frontiers

The role of α-ketoglutarate–dependent proteins in pluripotency acquisition and maintenance PMC - NIH

Metabolic Coordination of Cell Fate by α-Ketoglutarate-Dependent Dioxygenases PMC

Succinate inhibition of α-ketoglutarate-dependent enzymes in a yeast model of paraganglioma Human Molecular Genetics - Oxford Academic

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors PMC - PubMed Central

Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer AACR Journals

High-ammonia microenvironment promotes stemness and metastatic potential in hepatocellular carcinoma through metabolic reprogramming PubMed Central

Inducing autophagy: A comparative phosphoproteomic study of the cellular response to ammonia and rapamycin PMC - PubMed Central

Autophagy and ammonia PMC - NIH

Unfolded protein response in cancer: the Physician's perspective PMC

Endoplasmic Reticulum Stress and Cancer: Could Unfolded Protein Response Be a Druggable Target for Cancer Therapy? PMC - PubMed Central

Decoding Endoplasmic Reticulum Stress Signals in Cancer Cells and Anti-tumor Immunity PMC

Astragaloside IV Alleviates Ammonia-Induced Apoptosis and Oxidative Stress in Bovine Mammary Epithelial Cells MDPI

The Role of the ER-Induced UPR Pathway and the Efficacy of Its Inhibitors and Inducers in the Inhibition of Tumor Progression NIH

Senescence and senolysis in cancer: The latest findings PMC - PubMed Central

Ammonia production by GLS1 is essential for survival of senescent cells ResearchGate

Fusobacterium nucleatum: a new player in regulation of cancer development and therapeutic response NIH